Why Nano-Formulated Beverages?
Nanoemulsions have many advantages when it comes to the formulation of food and beverages including nutraceuticals and dietary supplements. Having a very small droplet size in the nano-range, nano-emulsions are kinetically stable colloidal systems.
For the formulation of nano-enhanced beverages, an oil-in-water (o/w) emulsion is required. In an oil-in-water (o/w) emulsion, the oil droplets are dispersed in an aqueous (water-based) phase. This kind of emulsion system is used for the delivery of hydrophobic active substances, e.g. CBD, vitamin E, vitamin A, antioxidants, essential oils and aroma compounds.
Without a reliable and powerful emulsifying agent, water-oil mixtures are not a long-term stable mixture and will separate.
Furthermore, many bioactive compounds such as cannabinoids (e.g., CBD, CBG, THC and terpenes), resveratrol, quercitin and vitamins show a very poor absorption rate and bioavailability when administered orally. The bioavailability and potency of such bioactive substances can be significantly improved when the substance is encapsulated in a nano-emulsion.
For cannabidiol or CBD, the well-known cannabis substance, which has anti-inflammatory, pain-reducing and sleep-promoting effects, the bioavailability is very poor, when not administered in water-soluble nano-form. In order to produce cannabis beverages with a high potency, the cannabinoids must be nano-emulsified.
Stuph emulsifier makes it easy to formulate beverages such as waters, isotonic sport drinks, soft drinks, coffees, dairy-based drinks and juices fortified with bioactive compounds such as cannabinoids, vitamins, lipids, flavours and other health-promoting substances.
Simplicity: Stuph-formulated nano-emulsions are ternary formulations comprising three phases: oil, water, and Stuph emulsifier. Fortification of beverages with nano-formulated bioactive compounds gets easy with Stuph!
Beverages, drinks, and tinctures can be fortified with nano-emulsified active ingredients, which have a very high bioavailability.
With Stuph emulsifier, cannabidiol (CBD) is made water-soluble so that it can be added to any water-based beverage, whilst offering great bioavailability!
- Improved bioavailability
- Improved absorption
- Improved pharmakokinetics
- Long-term stablility
- Clear appearance
- No interference with product aroma, taste and mouthfeel
- No off-flavour
- Improved shelf-life
Nano-Emulsions as Drug Carrier
To achieve a high absorption of poorly soluble nutrients and bioactive compounds into the cells, those bioactive substances must be formulated into a nanocarrier. Nano-emulsions function as nanocarrier or nano-drug-delivery vehicle and can be loaded with manifold phyto-chemicals and nutrients. Improved shelf-life: The incorporation of hydrophobic bioactive compounds into a nano-formulation such as a nano-emulsion protects the active substance against degradation through light, oxygen, high temperatures etc.
Typical molecules formulated into nano-emulsions include:
- phenolic compounds
- hydrophobic (water-insoluble) vitamins
- essential oils
- essential fatty acids